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　　許琛琦，研究員，1998年于華東師范大學獲得生物化學專業(yè)學士，2004年于中科院生化細胞所獲得生物化學與分子生物學博士學位，2004-2009年于哈佛大學Dana-Farber腫瘤研究所從事博士后研究，獲得Arthritis Foundation資助，后晉升為Instructor。2009年底加入中科院生化與細胞所，入選國家基金杰出青年基金。闡明了抗原免疫應答調(diào)控的新機制并發(fā)展了腫瘤免疫治療的新策略。工作已發(fā)表于Cell 2020, Nature 2018，Nature 2016，Nature 2013等，兩項成果入選中國科學十大進展/中國生命科學十大進展，其發(fā)明專利已成功進入轉(zhuǎn)化。榮獲上海市青年科技杰出貢獻獎(2020年)，中國青年科技獎(2018年)，中國生化與分子生物學會Promega生物化學獎(2018年)等榮譽。

• 　　圖3. 基于膽固醇代謝調(diào)控的腫瘤免疫治療新方法。膽固醇酯化酶ACAT1可以將細胞內(nèi)的游離膽固醇轉(zhuǎn)化為膽固醇酯。抑制CD8+ T細胞的ACAT1活性可以使細胞質(zhì)膜的游離膽固醇水平上升，從而使得TCR信號增強并讓殺傷性免疫突觸更成熟。T細胞腫瘤抗原免疫應答由此變得更加高效。

1. Jiang Y^#, Dai A^#, Huang Y^#, Li H^#, Cui J^#, Yang H, Si L, Jiao T, Ren Z, Zhang Z, Mou S, Zhu H, Guo W, Huang Q, Li Y, Xue M, Jiang J, Wang F, Li L, Zhong Q, Wang K, Liu B, Wang J, Fan G, Guo J, Chen L, Workman CJ, Shen Z^*, Kong Y^*, Vignali DAA^*,?Xu C^*, Wang H^*. Ligand-induced ubiquitination unleashes LAG3 immune checkpoint function by hindering membrane sequestration of signaling motifs.?Cell, 188(9):2354-2371.e18, 2025.
2. Xu XY^#, Chen H^#, Ren Z^#, Xu XM^#, Wu W, Yang H, Wang J, Zhang Y, Zhou Q, Li H, Zhang S, Wang H*,?Xu C*. Phase separation of chimeric antigen receptor promotes immunological synapse maturation and persistent cytotoxicity.?Immunity,?57(12): 2755-2771, 2024.
3. Shi X, He X, Xu C. Charge-based immunoreceptor signalling in health and disease.?Nature Reviews Immunology,?25(4):298-311, 2024.
4. Ren Z^#, Wang K^#, Zhang Y^#, Chen H, Zhu Y, Li H, Lou J^*, Wang H^*,?Xu C^*.?Transient hydroxycholesterol treatment restrains TCR signaling to promote long-term immunity.?Cell Chemical Biology, 31(5):920-931.e6, 2024.
5. Shi Y, Zheng X, Peng H,?Xu C, Sun R, Tian Z^*, Sun H^*, Wang X^*. The E3 Ubiquitin Ligase FBXO38 Maintains the Antitumor Function of Natural Killer Cells by Sustaining IL15R Signaling.?Cancer Immunology Research?12(10):1438-1451,2024.
6. Bai Y^#, Li T^#, Wang Q^#, You W^#,?Yang H,?Xu X, Li Z, Zhang Y, Yan C, Yang L, Qiu J, Liu Y, Chen S,?Wang D,?Huang B, Liu K, Song B, Wang Z, Li K, Liu X, Wang G, Yang W, Chen J, Hao P, Zhang Z, Wang Z^*, Zhu Z^*,?Xu C^*,?Shaping immune landscape of colorectal cancer by cholesterol metabolites,?EMBO Molecular Medicine?16(2):334-360, 2024.
7. Chen H^#, Xu X^#, Hu W^#, Wu S, Xiao J, Wu P, Wang X, Han X, Zhang YR Zhang Y, Jiang N, Liu W, Lou C, Chen W^*, Xu C^*, Lou J^*, Self-programmed dynamics of T cell receptor condensation, Proceedings of the National Academy of Sciences of the United States of America, 120(28):e2217301120, 2023.
8. Wang H^#*, Huang Y^#, Xu C^*, Charging CAR by Electrostatic Power, Immunological reviews, doi: 10.1111/imr.13232, 2023.
9. Yan C^#, Zheng L^#, Jiang S^#, Yang H^#, Guo J^#, Jiang L, Li T, Zhang H, Bai Y, Lou Y, Zhang Q, Liang T, Schamel W, Wang H, Yang W, Zhu Z, Song B^*, Xu C^*. Exhaustion-associated cholesterol deficiency dampens the cytotoxic arm of antitumor immunity. Cancer Cell, S1535-6108(23)00142-3, 2023.
10. Mo?s B, Li H, Molina-Ortiz P, Radermecker C, Rosu A, Catsyne C , Sayyed S, Fontela J, Duque M, Mostafa A, Azzi A, Barata J, Merino R, Xu C, Desmet C, Schurmans S. INPP5K controls the dynamic structure and signaling of wild type and mutated, leukemia-associated IL7 receptors. Blood, 141(14):1708-1717, 2023.
11. Wang X^#,?He X^#,?Jiang S^#,?Fu Z^#,?Jiang S,?Zhao X,?Zhao C,?Li Y,?Li D,?Zhang W,?Ai J^*,?Zhang Y^*,?Xu C^*,?Wang P^*. Limited enhancement of antibody and B-cell responses to prototype booster vaccination following SARS-CoV-2 Delta breakthrough infection. Journal of Medical Virology, 95(2):e28540, 2023.
12. Chen J^#, Qiu S^#, Li W^#, Wang K, Zhang Y, Yang H, Liu B, Li G, Li L, Chen M, Lan J, Niu J, He P, Cheng L, Fan G, Liu X, Song X^*, Xu C^*, Wu H^*, Wang H^*. Tuning Charge Density of Chimeric Antigen Receptor Optimizes CAR-T Cell Fitness. Cell Research, 33(5):341-354, 2023.
13. Ai J^#, Guo J^#, Zhang H^#, Zhang Y^#, Yang H^#, Lin K^#, Song J^#, Fu Z^#, Fan M^#, Zhang Q, Wang H, Zhao Y, He Z, Cui A, Zhou Y, Wu J, Zhou M, Yuan G, Kang B, Zhao N, Xu Y, Zhu M, Wang Y, Zhang Z, Jiang N^*, Qiu C^*, Xu C^*, Zhang W^*, Cellular basis of enhanced humoral immunity to SARS-CoV-2 upon homologous or heterologous booster vaccination analyzed by single-cell immune profiling, Cell Discovery, 8(1):114, 2022.
14. Wang X^#, Ai J^#, Li X^#, Zhao X^#, Wu J^#, Zhang H^#, He X^#, Zhao C, Qiao R, Li M, Cui Y, Hu Z^*, Xu C^*, Zhang W^* and Wang P^*, Neutralization of Omicron BA.4/BA.5 and BA.2.75 by booster vaccination or BA.2 breakthrough infection sera, Cell Discovery, 8(1):110, 2022.
15. Wang Q, Zhu T, Miao N, Qu Y, Wang Z, Chao Y, Wang J, Wu W, Xu X, Xu C, Xia L, Wang F, Disulfiram bolsters T-cell anti-tumor immunity through direct activation of LCK-mediated TCR signaling, The EMBO Journal, 41(16):e110636, 2022
16. Pathan-Chhatbar S?, Drechsler C, K,Morath? A, Wu W, OuYang B, Xu C, Schamel? W*, Direct Regulation of the T Cell Antigen Receptor's Activity by Cholesterol. Frontiers in Cell and Developmental Biology, 8:615996, 2021
17. Wen M#*, Cao Y#, Wu B#, Xiao T, Cao R, Wang Q, Liu X, Xue H, Yu Y, Lin J,?Xu C, Xu J, OuYang B*,?PD-L1 degradation is regulated by electrostatic membrane association of its cytoplasmic domain.?Naturer Communications,?12(1):5106, 2021.
18. Xu Y, Ma J, Luo H, Shi Y, Liu H, Sun A,?Xu C, Ji H, Liu X,?Chromatin assembly factor 1B critically controls the early development but not function acquisition of invariant natural killer T cells in mice.?Eur J Immunol. 51(7):1698-1714, 2021
19. Wang H*, Song X, Shen L, Wang X, Xu C*,?Exploiting T cell signaling to optimize engineered T cell therapies,?Trends?in?Cancer, S2405-8033(21)00224-7, 2021.
20. Li T#, Cai H#, Zhao Y#, Li Y#, Lai Y#, Yao H#, Liu L# , Sun Z#, Vlissingen M, Kuiken T, GeurtsvanKessel C , Zhang N , Zhou B , Lu L , Gong Y, Qin W , MondalM , Duan B , Xu S , Richard A, Raoul H , Chen J, Xu C, Wu L , Zhou H , Huang Z , Zhang X , Li J , Wang Y , Bi Y , Rockx B , Chen J*, Meng F*, Lavillette D*, Li D*, Uncovering a conserved vulnerability site in SARS-CoV-2 by a human antibody，EMBO Molecular Medicine ,13(12):e14544, 2021
21. Delgoffe G, Xu C, Mackall C, Green M, Gottschalk S, Speiser D, Zehn D, Beavis P, The role of exhaustion in CAR T cell therapy. Cancer Cell, 39: 888, 2021.
22. Wu W^#, Zhou Q^#, Masubuchi T^#, Shi X^#, Li H, Xu X, Huang M, Meng L, He X, Zhu H, Gao S, Zhang N, Jing R, Sun J, Wang H, Hui E*, Wong C^*, Xu C^*, Multiple signaling roles of CD3e and its application in CAR-T cell therapy. Cell, 182(4): 855-871.e23, .2020.
23. Li W^#, Qiu S^#, Jian C^#, Jiang S, Chen W, Jiang J, Wang F, Si W, Shu Y, Wei P, Fan G, Tian R, Wu H^*, Xu C^*, Wang H^*, Chimeric Antigen Receptor Designed to Prevent Ubiquitination and Downregulation Showed Durable Antitumor Efficacy. Immunity, 53(2):456-470.e6. 2020.
24. He X, Xu C^*, Immune checkpoint signaling and cancer immunotherapy. Cell Research, 30(8): 660-669, 2020.
25. Guo J, Xu C^*, Screening for the next-generation T cell therapies. Cancer Cell, 37(5): 627-629, 2020.
26. Fan Z^#, Tian Y^#, Chen Z, Liu L, Zhou Q, He J, Coleman J, Dong C, Li N, Huang J, Xu C, Zhang Z, Gao S, Zhou P^*, Ding K^*, Chen L^*, Blocking interaction between SHP2 and PD-1 denotes a novel opportunity for developing PD-1 inhibitors. EMBO molecular medicine, e11571, 2020.
27. He X, Xu C^*, PD-1: A Driver or Passenger of T Cell Exhaustion? Molecular Cell, 77(5): 930-931, 2020.
28. Huang B, Song B, Xu C^*. Cholesterol metabolism in cancer: mechanisms and therapeutic opportunities. Nature Metabolism, 2: 132-141, 2020.
29. Xu X^#, Li H^#, Xu, C^*. Structural understanding of T cell receptor triggering. Cellular & Molecular Immunology, 17(3): 193-202, 2020.
30. Xu C^*, Li HB^*, Flavell RA^*, A special collection of reviews on frontiers in immunology. Cell Research, 30(10):827-828, 2020.
31. Sun A^#, Xu K^#, Liu H, Li H, Shi Y, Zhu X, Liang T, Li X, Cao X, Ji Y, Jiang T, Xu C, Liu X^*, The evolution of zebrafish RAG2 protein is required for adapting to the elevated body temperature of the higher endothermic vertebrates. Scientific reports, 10(1):4126, 2020.
32. Li H^*, Yan C, Guo J, Xu C^*. Ionic protein–lipid interactions at the plasma membrane regulate the structure and function of immunoreceptors. Advances in Immunology, 144 pp 65-85, 2019.
33. Wu P, Zhang T, Liu B, Fei P, Cui L, Qin R, Zhu H, Yao D, Martinez R, Hu W, An C, Zhang Y, Liu J, Shi J, Fan J, Yin W, Sun J, Zhou C, Zeng X, Xu C, Wang J, Evavold B, Zhu C, Chen W^*, Lou J^*. Mechano-regulation of Peptide-MHC Class I Conformations Determines TCR Antigen Recognition. Molecular Cell. 73(5):1015-1027, 2019.
34. Meng X^#, Liu X^#, Guo X, Jiang S, Chen T, Hu Z, Liu H, Bai Y, Xue M, Hu R, Sun SC, Liu X, Zhou P, Huang X, Wei L, Yang W, Xu C^*. FBXO38 mediates PD-1 ubiquitination and regulates anti-tumour immunity of T cells. Nature. 564 (7734): 130-135, 2018.
35. Guo J^#, Zhang Y^#, Li H^#, Chu H^#, Wang Q, Jiang S, Li Y, Shen H, Li G^*, Chen J^*, Xu C^*. Intramembrane ionic protein-lipid interaction regulates integrin structure and function. PLoS Biology, 16(11): e2006525, 2018.
36. Chen X^#, Sun X^#, Yang W^#, Yang B^#, Zhao X, Chen S, He L, Chen H, Yang C, Xiao L, Chang Z, Guo J, He J, Zhang F, Zheng F, Hu Z, Yang Z, Lou J, Zheng W, Qi H, Xu C, Zhang H, Shan H, Zhou XJ, Wang Q, Shi Y, Lai L, Li Z^*, Liu W^*. An autoimmune disease variant of IgG1 modulates B cell activation and differentiation. Science. 362 (6415): 700-705, 2018.
37. Wang J, Yan C, Xu C, Chua B, Li P^*, Chen F^*. Polybasic RKKR motif in the linker region of lipid droplet (LD)-associated protein CIDEC inhibits LD fusion activity by interacting with acidic phospholipids. Journal of Biological Chemistry. 293(50):19330-19343, 2018.
38. Xu C, Xie H, Guo X, Gong H, Liu L, Qi H, Xu C, Liu W^*. A PIP2-derived amplification loop fuels the sustained initiation of B cell activation. Science Immunology, 2(17), 2017.
39. Bietz A^#, Zhu H^#, Xue M, Xu C^*. Cholesterol Metabolism in T Cells. Frontiers in Immunology, 8:1664, 2017.
40. Yang W^#, Pan W^#, Chen S^#, Trendel N^#, Jiang S^#, Xiao F, Xue M, Wu W, Peng Z, Li X, Ji H, Liu X, Jiang H, Wang H, Shen H, Dushek O^*, Li H^*, Xu C^*. Dynamic regulation of CD28 conformation and signaling by charged lipids and ions. Nature Structural and Molecular Biology, 24 (12): 1081-1092, 2017.
41. Wang H, Wang S, Li C, Li H, Mao Y, Liu W, Xu C^*, Long D^*. Probing Transient Release of Membrane-Sequestered Tyrosine-Based Signaling Motif by Solution NMR Spectroscopy. Journal of Physical Chemistry Letters, 8(16): 3765-3769, 2017.
42. Li L^#, Guo X^#, Shi X^#, Li C^#, Wu W, Yan C, Wang H, Li H, Xu C^*. Ionic CD3-Lck interaction regulates the initiation of T-cell receptor signaling. Proc Natl Acad Sci U S A, 114(29): E5891-E5899, 2017.
43. Guo X^#, Yan C^#, Li H^#, Huang W^#, Shi X, Huang M, Wang Y, Pan W, Cai M, Li L, Wu W, Bai Y, Zhang C, Liu Z, Wang X, Zhang F X, Tang C, Wang H, Liu W, Ouyang B, Catherine C Wong, Cao Y^*, Xu C^*. Lipid-dependent conformational dynamics underlie the functional versatility of T-cell receptor. Cell Research, 27(4): 505-525, 2017.
44. Yang W^#, Bai Y^#, Xiong Y, Zhang J, Chen S, Zheng X, Meng X, Li L, Wang J, Xu C, Yan C, Wang L, Chang C, Chang T, Zhang T, Zhou P Song B, Liu W, Sun S, Liu X, Li B^*, Xu C^*. Potentiating the antitumour response of CD8⁺ T cells by modulating cholesterol metabolism. Nature, 531 (7596): 651-655, 2016.
45. Wu W, Shi X, Xu C^*. Regulation of T cell signalling by membrane lipids. Nature Reviews Immunology, 16 (11): 690-701, 2016.
46. Xu L^#, Xia M^#, Guo J^#, Sun X^#, Li H, Xu C, Gu X, Zhang H, Yi J, Fang Y, Xie H, Wang J, Shen Z, Xue B, Sun Y, Meckel T, Chen YH, Hu Z, Li Z^*, Xu C^*, Gong H^*, Liu W^*. Impairment on the lateral mobility induced by structural changes underlies the functional deficiency of the lupus-associated polymorphism FcγRIIB-T232. Journal of Experimental Medicine. 213 (12): 2707-2727, 2016.
47. Liu W^*, Wang H, Xu C^*. Antigen Receptor Nanoclusters: Small Units with Big Functions. Trends in Immunology. 37 (10): 680-689, 2016.
48. Cui Y^#, Chen X^#, Zhang J, Sun X, Liu H, Bai L, Xu C, Liu X^*. Uhrf1 Controls iNKT Cell Survival and Differentiation through the Akt-mTOR Axis. Cell Reports, 15(2): 256-263, 2016.
49. Chen X ^#, Pan W^#, Sui Y, Li H, Shi X, Guo X, Qi H, Xu C^*, Liu W^*. Acidic phospholipids govern the enhanced activation of IgG-B cell receptor. Nature Communications, 6 (8552), 2015.
50. Liu C^#, Zhao X^# Xu L, Yi J, Shaheen S, Han W, Wang F, Zheng W, Xu C, Liu W. A negative-feedback function of PKCβ in the formation and accumulation of signaling-active B cell receptor microclusters within B cell immunological synapse. Journal of Leukocyte Biology, 97(5): 887-900, 2015
51. Wu W^#, Yan C^#, Shi X, Li L, Liu W, Xu C^*. Lipid in T-cell receptor transmembrane signaling. Progress in Biophysics and Molecular Biology, 118(3): 130-138, 2015.
52. Wang Y^#, Gao J^#, Guo X^#, Tong T, Shi X, Li L, Qi M, Wang Y, Cai M, Jiang J, Xu C^*, Ji H^*, Wang H^*. Regulation of EGFR nanocluster formation by ionic protein-lipid interaction. Cell Research, 24(8): 959-976, 2014.
53. Li L^#, Shi X^#, Guo X, Li H, Xu C^*. Ionic protein-lipid interaction at the plasma membrane: what can the charge do? Trends in Biochemical Sciences, 39(3): 130-140, 2014.
54. Wertek F, Xu C^*. Digital response in T cells: to be or not to be. Cell Research, 24(3): 265-266, 2014.
55. Li P, Fu Z, Zhang Y, Zhang J, Xu C, Ma Y, Li B, Song B. The clathrin adaptor Numb regulates intestinal cholesterol absorption through dynamic interaction with NPC1L1. Nature Medicine, 20(1): 80-86, 2014.
56. Shi X^#, Bi Y^#, Yang W^#, Guo X, Jiang Y, Wan C, Li L, Bai Y, Guo J, Wang Y, Chen X, Wu B, Sun H, Liu W, Wang J^*, Xu C^*. Ca²⁺ regulates T-cell receptor activation by modulating the charge property of lipids. Nature, 493(7430): 111-115, 2013.
57. Liu B^#, Liu Y^#, Du Y, Mardaryev A, Yang W, Chen H, Xu Z, Xu C, Zhang X, Botchkarev V, Zhang Y^*, Xu G^*. Cbx4 regulates the proliferation of thymic epithelial cells and thymus function. Development, 140(4): 780-788, 2013.
58. Zhang K^#, Pan Y^#, Qi J, Yue J, Zhang M, Xu C, Li G^*, Chen J^*. Disruption of disulfide-restriction at integrin knees induces activation and ligand-independent signaling of α4β7. Journal of Cell Science, 126(Pt21): 5030-5041, 2013.
59. Wang X^#, Jimenez-Vargas J^#, Xu C, Possani L^*, Zhu S^*. Positive selection-guided mutational analysis revealing two key functional sites of scorpion ERG K(+) channel toxins. Biochemical and Biophysical Research Communications, 429(1-2): 111-116, 2012.
60. Gagnon E, Xu C, Yang W, Chu H, Call M, Chou J, Wucherpfennig K^*. Response multilayered control of T cell receptor phosphorylation. Cell, 142(5): 669-671, 2010.
61. Xu C^#, Gagnon E^#, Call M, Schnell J, Schwieters C, Carman C, Chou J^*, Wucherpfennig K^*. Regulation of T cell Receptor Activation by Dynamic Membrane Binding of the CD3e Cytoplasmic Tyrosine-Based Motif. Cell, 135(4): 702-713, 2008.
62. Wang S, Huang L, Wicher D, Chi C^*, Xu C^*. Structure-function relationship of bifunctional scorpion toxin BmBKTx1. Acta Biochimica et Biophysica Sinica (Shanghai), 40(11): 955-963, 2008.
63. O’Connor K^#, McLaughlin KA^#, De Jager P, Chitnis T, Bettelli E, Xu C, Robinson W, Cherry S, Bar-Or A, Banwell B, Fukaura H, Fukazawa T, Tenembaum S, Wong S, Tavakoli N, Idrissova Z, Viglietta V, Rostasy K, Pohl D, Dale R, Freedman M, Steinman L, Buckle G, Kuchroo V, Hafler D^*, Wucherpfennig K^*. Self-antigen tetramers discriminate between myelin autoantibodies to native or denatured protein. Nature Medicine, 13(2): 211-217, 2007.
64. Xu C, Call M, Wucherpfennig K. A membrane-proximal tetracysteine motif contributes to assembly of cd3de and cd3ge dimers with the T cell receptor. Journal of Biological Chemistry, 281(48): 36977-36984, 2006.
65. Call M^#, Schnell J^#, Xu C, Lutz R, Chou J^*, Wucherpfennig K^*. The Structure of the ζζ Transmembrane Dimer Reveals Polar Features Essential for Dimerization and Assembly with the T cell Receptor. Cell, 127(2): 355-368, 2006.
66. Jiang H, Xu C, Wang C, Fan C, Zhao T, Chen J, Chi C. Two novel O-superfamily conotoxins from Conus vexillum. Toxicon, 47(4): 425-436, 2006.
67. Jiang H^#, Wang C^#, Xu C, Fan C, Dai X, Chen J, Chi C. A novel M-superfamily conotoxin with a unique motif from Conus vexillum. Peptides, 27(4): 682-689, 2006.
68. Xu C^#, Br？ne B^#, Wicher D, Bozkurt O, Lu W, Huys I, Han Y, Tytgat J, Van Kerkhove E, Chi C. BmBKTx1, a novel Ca²⁺activated K⁺ channel blocker purified from the Asian scorpion Buthus martensi Karsch. Journal of Biological Chemistry, 279(33): 34562-34569, 2004.
69. Xu C, He L, Br？ne B, Martin-Eauclaire M, Van Kerkhove E, Zhou Z, Chi C. A novel scorpion toxin blocking small conductance Ca²⁺ activated K⁺ channel. Toxicon, 43(8): 961-971, 2004.
70. Cai Z^#, Xu C^#, Xu Y, Lu W, Chi C, Shi Y, Wu J. Solution structure of BmBKTx1, a new BKCa1 channel blocker from the Chinese scorpion Buthus martensi Karsch. Biochemistry, 43(13): 3764-3771, 2004.
71. Huys I^#, Xu C^#, Wang C, Vacher H, Martin-Eauclaire M, Chi C, Tytgat J. BmTx3, a scorpion toxin with two putative functional faces separately active on A-type K⁺ and HERG currents. Biochemical Journal, 378(3): 45-52, 2004.
72. Frénal K^#, Xu C^#, Wolff N, Wecker K, Gurrola G, Zhu S, Chi C, Possani L, Tytgat J^*, Delepierre M^*. Exploring structural features of the interaction between the scorpion toxinCnErg1 and ERG K⁺ channels. PROTEINS: Structure, Function, and Bioinformatics, 56(2): 367-375, 2004.
73. Szyk A, Lu W, Xu C, Lubkowski J. Structure of the Scorpion Toxin BmBKTx1 Solved from Single Wavelength Anomalous Scattering of Sulfur. Journal of Structural Biology, 145(3): 289-294, 2004.
74. Xu C, Zhu S, Chi C, Tytgat J. Turret and pore block of K⁺ channels: what is the difference? Trends in Pharmacological Sciences, 24(9): 446-448, 2003.

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