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　　1993-1998 年安徽醫(yī)科大學(xué)臨床醫(yī)學(xué)系本科;1998-2001 年安徽醫(yī)科大學(xué)免疫系和中國(guó)預(yù)防醫(yī)學(xué)科學(xué)院病毒所基因工程國(guó)家重點(diǎn)實(shí)驗(yàn)室聯(lián)合培養(yǎng)碩士;2001-2006 英國(guó)倫敦帝國(guó)理工學(xué)院(Imperial College London)博士及Research Associate; 2006-2010 英國(guó)劍橋大學(xué)Research Fellow;2010年3月任生化與細(xì)胞所研究員，研究組長(zhǎng);2011年入選上海市浦江人才計(jì)劃。2014年獲國(guó)家基金委優(yōu)秀青年資助。2018年獲國(guó)家自然基金委杰出青年資助。2015年獲中國(guó)科學(xué)院優(yōu)秀指導(dǎo)老師稱(chēng)號(hào)。

1. J Xiao*, S Wang*, LL Chen*, XY Ding, MS Han, YX Zheng, MC Wang, D Yang, N Li, C Dong, H Shen, SF Wu, M Hu, C Su, WY Li, LJ Hui, YQ Ye#, HR Tang#, B Wei#, HY Wang#. 25-Hydroxycholesterol regulates lysosome AMPK activation and metabolic reprogramming to educate immunosuppressive macrophages, Immunity. 2024 Accept
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5. D Yang, TK Tian, XJ Li, BK Zhang, LL Qi, F Zhang, MS Han, S Wang, J Xiao, YY Gou, RR Zhang, QJ Liu, S Su, JH Liu, XW Huang, Q Gao, LJ Hui, HR Tang, HY Wang#, B Wei#. ZNT1 and Zn2+ control TLR4 and PD-L1 endocytosis in macrophage to improve chemotherapy efficacy against liver tumor, Hepatology.?2023 Oct 9.?Online ahead of print.
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9. C Zhang*, WY Li *, XB Lei, ZF Xie, LL Qi, H Wang, X Xiao, J Xiao, YX Zheng, C Dong, X Zheng, SY Chen, JF Chen, B Sun, J Qin, QW Zhai, JS Li, B Wei#, JW Wang#, HY Wang#. Targeting lysophospholipid acid receptor 1 and ROCK kinases promotes antiviral innate immunity. Sci Adv. 2021 Sep 17;7(38): eabb5933.
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11. ZQ Li*, J Xiao*, XY Xu*, WY Li*, RY Zhong, LL Qi, JH Chen, GZ Cui, S Wang, YX Zheng, Y Qiu, S Li, X Zhou, Y Lu, JY Lyu, B Zhou, JW Zhou, NH Jing, B Wei#, J Hu#, HY Wang#. M-CSF, IL-6 and TGF-β promotes generation of a new subset of tissue repair macrophages for traumatic brain injury recovery. Sci Adv. 2021 Mar 12;7(11): eabb6260.
12. J Xiao*, WY Li *, X Zheng, LL Qi, H Wang, C Zhang, XP Wan, YX Zheng, RY Zhong, X Zhou, Y Lu, ZQ Li, Y Qiu, C Liu, F Zhang, YB Zhang, XY Xu, ZZ Yang, HL ?Chen, QW Zhai, B Wei#, Hongyan Wang #. Targeting 7-Dehydrocholesterol Reductase Integrates Cholesterol Metabolism and IRF3 Activation to Eliminate Infection. Immunity. 2020 Jan 14;52(1):109-122.e6.
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14. Q Wang^*, X Zhou^*, L Yang^*, YJ Zhao, ZH Chew, J Xiao, C Liu, X Zheng, YX Zheng, Q Shi,, QQ Liang^#, YJ Wang ^#*, H Wang^#. The natural compound Notopterol binds and targets JAK2/3 to ameliorate inflammation and arthritis. Cell Reports 2020;32:108158
15. Y Lu^*, Y Qiu^*, P Chen, H Chang, L Guo, F Zhang, L Ma, C Zhang, X Zheng, J Xiao, R Zhong, L Han, X Xu, Y Zhang, D Li, G Zhong, R Boyton, Y Huang, Y He, R Hu^#, B Wei^#, H Wang^# The ER-localised Hrd1 ubiquitinates and inactivates Usp15 to promote TLR4-induced inflammation during bacterial infection. Nature Microbiology, 2019,4:2331-46
16. X Zhou, WY Li S Wang, P Zhang, Q Wang, J Xiao, C Zhang, X Zheng, X Xu, S Xue, L Hui, H Ji, B Wei#, H Wang#. YAP aggravates inflammatory bowel disease (IBD) via regulating M1/M2 macrophage polarization and gut microbial homeostasis. Cell Reports, 2019, 27;1176-89
17. T Zhou#, MC Luo*, W Cai, SY Zhou, DY Feng, CD Xu, H. Wang#. Runt-related transcription factor 1 (RUNX1) promotes TGF-β-induced renal tubular epithelial-to-mesenchymal transition (EMT) and renal fibrosis through the PI3K subunit p110δ. EBioMedicine, 2018.31:217-225
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21. Luo MC^*, Zhou SY^*, Feng DY, Xiao J, Li WY, Xu CD, Wang HY#, Zhou T#. Runt-related Transcription Factor 1 (RUNX1) Binds to p50 in Macrophages and Enhances TLR4-triggered Inflammation and Septic Shock. J Biol Chem. 2016;291 (42), 22011-22020.
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