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科研成果

科研成果

uo Liu,Hengwei Jin,Shaohua Zhang,Muxue Tang,Xinfeng Meng,Yan Li,Wenjuan Pu,Kathy O Lui,Bin Zhou,Intercellular genetic tracing of cardiac endothelium in the developing heart,Dev Cell2023 Jun 21.
Kuo Liu,Muxue Tang,Wei Xu,Xinfeng Meng,Hengwei Jin,Maoying Han,Jing Pu,Yutang Li,Fanke Jiao,Ruilin Sun,Ruling Shen,Kathy O Lui,Lu Lu,Bin Zhou,An inducible hACE2 transgenic mouse model recapitulates SARS-CoV-2 infection and pathogenesis in vivo,Proc Natl Acad Sci U S A2023 Jun 12.
Guoqing Cai,Yijun Qi,Ping Wei,Hong Gao,Chenqi Xu,Yun Zhao,Xiujuan Qu,Feng Yao,Weiwei Yang,IGFBP1 Sustains Cell Survival during Spatially-Confined Migration and Promotes Tumor Metastasis,Adv Sci2023 Jun 9.
Siqi Gao,Hanwen Zhu,Kangwen Cai,Leiqin Liu,Zhiqiang Zhang,Yi Ding,Yaochen Xu,Xiaoqi Zheng,Jiantao Shi,TRAmHap: accurate prediction of transcriptional activity from DNA methylation haplotypes in bisulfite-sequencing data,Brief Bioinform2023 Jun 2.
Xiuxiu Liu,Wendong Weng,Lingjuan He,Bin Zhou,Genetic recording of in vivo cell proliferation by ProTracer,Nat Protoc2023 Jun 2.
Chengsong Yan,Lin Zheng,Shutan Jiang,Haochen Yang,Jun Guo,Luyi Jiang,Tongzhou Li,Haosong Zhang,Yibing Bai,Yu Lou,Qi Zhang,Tingbo Liang,Wolfgang Schamel,Haopeng Wang,Weiwei Yang,Guangchuan Wang,Zhengjiang Zhu,Baoliang Song,Chenqi Xu,Exhaustion-associated cholesterol deficiency dampens the cytotoxic arm of antitumor immunity,Cancer Cell2023 May 23.
Songling Zhu,Shufen Zhong,Kebin Cheng,Lisha Zhang,Jiuwu Bai,Zu Cao,Su Wang,Wen Chen,Shipeng Cheng,Liyan Ma,Zhiyang Ling,Yuying Huang,Wangpeng Gu,Xiaoyu Sun,Chunyan Yi,Meng Zhao,Shuo Liang,Jinfu Xu,Bing Sun,Yaguang Zhang,itamin B6 regulates IL-33 homeostasis to alleviate type 2 inflammation,Cell Mol Immunol2023 May 23.
Qing Li,Jiansen Lu,Xidi Yin,Yunjian Chang,Chao Wang#,Meng Yan,Li Feng,Yanbo Cheng,Yun Gao,Beiying Xu,Yao Zhang,Yingyi Wang,Guizhong Cui,Luang Xu,Yidi Sun,Rong Zeng,Yixue Li,Naihe Jing,Guoliang Xu,Ligang Wu,Fuchou Tang,Jinsong Li,Base editing-mediated one-step inactivation of the Dnmt gene family reveals critical roles of DNA methylation during mouse gastrulation,Nat Commun2023 May 22.
Yanyan Wang,Senxin Zhang,Xinrui Yang,Joyce K. Hwang,Chuanzong Zhan,Chaoyang Lian,Chong Wang,Tuantuan Gui,Binbin Wang,Xia Xie,Pengfei Dai,Lu Zhang,Ying Tian,Huizhi Zhang,Chong Han,Yanni Cai,Qian Hao,Xiaofei Ye,Xiaojing Liu,Jiaquan Liu,Zhiwei Cao,Shaohui Huang,Jie Song,Qiang Pan-Hammarstrom,Yaofeng Zhao,Frederick W. Alt,Xiaoqi Zheng,Lintai Da,Leng-Siew Yeap,Feilong Meng,Mesoscale DNA feature in antibody-coding sequence facilitates somatic hypermutation,Cell2023 Apr 24.
Yifan Wang,Qiang Zheng,Zhen Sun,Chenhua Wang,Jin Cen,Xinjie Zhang,Yan Jin,Baihua Wu,Tingting Yan, Ziyuan Wang,Qiuxia Gu,Xingyu Lv,Junjie Nan,Zhongyu Wu,Wenbin Sun,Guoyu Pan,Ludi Zhang,Lijian Hui,Xiujun Cai,Reversal of liver failure using a bioartificial liver device implanted with clinical-grade human induced hepatocytes,Cell Stem Cell2023 Apr 13.
Shijie Tang,Yun Xue,Zhen Qin, Zhaoyuan Fang,Yihua Sun,Chongzhe Yuan,Yunjian Pan,Yue Zhao,Xinyuan Tong,Jian Zhang,Hsinyi Huang,Yuting Chen,Liang Hu,Dasong Huang,Ruiqi Wang,Weiguo Zou,Yuan Li,Roman K Thomas,Andrea Ventura,Kwok-Kin Wong,Haiquan Chen,Luonan Chen,Hongbin Ji,Counteracting lineage-specific transcription factor network finely tunes lung adeno-to-squamous transdifferentiation through remodeling tumor immune microenvironment,Natl Sci Rev2023 Feb 14.
Xiaojie Cai,Maoying Han,Fangzhou Lou,Yang Sun,Qianqian Yin,Libo Sun,Zhikai Wang,Xiangxiao Li, Hong Zhou,Zhenyao Xu,Hong Wang,Siyu Deng,Xichen Zheng,Taiyu Zhang,Qun Li,Bin Zhou,Honglin Wang,Tenascin C+ papillary fibroblasts facilitate neuro-immune interaction in a mouse model of psoriasis,Nat Commun2023 Apr 10.
Licong He,Qiaoyu Zhao,Jianzhong Qi,Yifan Wang,Wenyu Han,Zhangcheng Chen,Yao Cong,Sheng Wang,Structural insights into constitutive activity of 5-HT6 receptor,Proc Natl Acad Sci U S A2023 Mar 29.
Maoying Han,Zixin Liu,Lei Liu,Xiuzhen Huang,Haixiao Wang,Wenjuan Pu,Enci Wang,Xiuxiu Liu,Yan Li,Lingjuan He,Xufeng Li,Jiayu Wu,Lin Qiu,Ruling Shen,Qingdong Wang,Yong Ji,Reza Ardehali,Qiang Shu,Kathy O. Lui,Lixin Wang,Bin Zhou,Dual genetic tracing reveals a unique fibroblast subpopulation modulating cardiac fibrosis,Nat Genet2023 Mar 23.
Wenyu Han,Mingliang Jin,Caixuan Liu,Qiaoyu Zhao,Shutian Wang,Yifan Wang,Yue Yin,Chao Peng,Yanxing Wang,Yao Cong,Structural basis of plp2-mediated cytoskeletal protein folding by TRiC/CCT,Sci Adv2023 Mar 15.
Wenjuan Pu,Huan Zhu,Mingjun Zhang,Monika Pikiolek,Caner Ercan,Jie Li,Xiuzhen Huang,Ximeng Han,Zhenqian Zhang,Zan Lv,Yan Li,Kuo Liu,Lingjuan He,Xiuxiu Liu,Markus H. Heim,Luigi M. Terracciano,Jan S. Tchorz,Bin Zhou,Bipotent transitional liver progenitor cells contribute to liver regeneration,Nat Genet2023 Mar 13.
Lin Shan,Guang Xu,Runwen Yao,Pengfei Luan,Youkui Huang,Peihong Zhang,Yuhang Pan,Lin Zhang,Xiang Gao,Ying Li,Shimeng Cao,Shuaixin Gao,Zhenghu Yang,Siqi Li,Liangzhong Yang,Ying Wang,Catharine C. L. Wong,Li Yu,Jinsong Li,Li Yang,Lingling Chen,Nucleolar URB1 ensures 3' ETS rRNA removal to prevent exosome surveillance,Nature2023 Mar 8.
Jian Chen,Shizhen Qiu,Wentao Li,Kun Wang,Yu Zhang,Han Yang,Baichuan Liu,Guangfei Li,Li Li,Min Chen,Junjie Lan,Jiahua Niu,Peijie He,Lei Cheng,Gaofeng Fan,Xin Liu,Xianmin Song,Chenqi Xu,Haitao Wu,Haopeng Wang,Tuning charge density of chimeric antigen receptor optimizes tonic signaling and CAR-T cell fitness,Cell Res2023 Mar 8.
Mengwen Huang,Xingchao Pan,Xinling Wang,Qingfei Ren,Bei Tong,Xianchi Dong,Gaoxiang Ge,Lu Lu,Shibo Jiang,Jianfeng Chen,Lymphocyte integrins mediate entry and dysregulation of T cells by SARS-CoV-2,Signal Transduct Target Ther2023 Feb 27.
Zhishuo Wang,Chenghua Yan,Qizhen Du,Yuying Huang,Xuezhen Li,Dan Zeng,Ruizhi Mao,Rama Krishna Gurram,Shipeng Cheng,Wangpeng Gu,Lin Zhu,Weiguo Fan,Liyan Ma,Zhiyang Ling,Ju Qiu,Dangsheng Li,Enmei Liu,Yaguang Zhang,Yiru Fang,Jinfang Zhu,Bing Sun,HTR2A agonists play a therapeutic role by restricting ILC2 activation in papain-induced lung inflammation,Cell Mol Immunol2023 Feb 24.

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